PANS/PANDAS Symptom Severity

Symptom Severity

The severity of PANS various from patient to patient.

Some children suffer debilitating flares while others function enough to continue to go to school but not remotely at the same functioning level. PANS/PANDAS symptoms may relapse and remit. During subsequent flares, symptoms can worsen and new symptoms may manifest. Some children do not return to pre-PANS baseline level in between flares; some symptoms clear completely during treatment while some may take longer to resolve. 

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Treatment Guidelines Published for PANS/PANDAS

Treatment guidelines developed by the PANS/PANDAS Research Consortium are now available in the Journal of Child and Adolescent Psychopharmacology. The guidelines address:

1. Psychiatric medications and behavioral interventions
2. Antimicrobials
3. Anti-inflammatory and immunomodulating therapies.

“The three sets of guidelines truly represent ‘best practices’ from across the country.”

Overview of Treatment of Pediatric Acute-Onset Neuropsychiatric Syndrome, Swedo Susan E., Frankovich Jennifer, and Murphy Tanya K.

JCAP Treatment Guidelines